Extending the CHASTE simulation library, comparing vertex dynamics and cellular Potts model
نویسنده
چکیده
Many mathematical models of biological cells exist. Among the most powerful for modelling the detailed interactions and geometry of individual cells are vertex dynamics models, commonly used for epithelial sheets. In this project we develop extensions to CHASTE (Cancer, Heart and Soft Tissue Environment, http://www.cs.ox.ac.uk/chaste/), an open-source modelling software developed at the University of Oxford, that includes vertex dynamics models, to facilitate future simulations. We also compare qualitative and quantitative characteristics of the vertex dynamics models to the cellular Potts model.
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